NAGA Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 15096-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells

Positive IHC detected in:
human placenta tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2400
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
N-acetylgalactosaminidase, alpha-

Calculated molecular weight:
47 kDa

Observed molecular weight:
48 kDa,60-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NAGA

Synonyms
Alpha galactosidase B, D22S674, GALB, NAGA
Background

NAGA belongs to the glycosyl hydrolase 27 family. It removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. It is required for the breakdown of glycolipids. Biosynthetic studies performed with cultured fibroblasts indicated that the human enzyme was synthesized as a 65kDa glycosylated precursor which was processed to a mature 48-kDa lysosomal form; both the precursor and mature forms had high mannose type oligosaccharide chains, but only the precursor’s mannose residues were phosphorylated. 90-117kd is a homodimer of NAGA.


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