NOX5 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 25350-1-AP

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Freight/Packing

Con: 51 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells, Raji cells

Positive IHC detected in:
human testis tissue, human spleen tissue, human testis tissue

Positive IF detected in:
RAW 264.7 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
NADPH oxidase, EF-hand calcium binding domain 5

Calculated molecular weight:
765aa,86 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NOX5

Synonyms
NADPH oxidase 5, NOX5, NOX5A, NOX5B
Background

NOX5 (NADPH oxidase, EF-hand calcium binding domain 5) is an NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca(2+)-dependent manner. It plays an important role in PDGF-induced JAK/STAT activation and human aortic smooth muscle cell (HASMC) proliferation. NOX5 is the main source of superoxide and is implicated in human spermatozoa motility. This protein has 6 isoforms produced by alternative splicing, named NOX5-α, -β, -γ, -δ, -ε and -ζ with the molecular mass of 84, 82, 86, 85, 64 and 83 kDa (PMID: 22427510 and Uniprot).


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