NRAS Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 10724-1-AP

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Freight/Packing

Con: 41 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, A431 cells, C6 cells, Jurkat cells, NIH/3T3 cells

Positive IHC detected in:
human pancreas tissue, human testis tissue

Positive IF detected in:
HeLa cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
neuroblastoma RAS viral (v-ras) oncogene homolog

Calculated molecular weight:
21 kDa

Observed molecular weight:
21 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NRAS

Synonyms
ALPS4, GTPase NRas, HRAS1, N ras, NRAS, NRAS1, Transforming protein N Ras
Background

NRAS, also named as N-ras and NRAS1, is neuroblastoma RAS viral (v-ras) oncogene homolog from the mammalian ras gene family and it is a member of the small GTPase superfamily. RAS proteins are involved in signal transduction pathways, and bind GDP/GTP and possess intrinsic GTPase activity. It is mapped on chromosome 1, and it is activated in HL60, a promyelocytic leukemia line. Defects in NRAS are a cause of juvenile myelomonocytic leukemia (JMML).


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