TXNL6 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 11203-1-AP

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Freight/Packing

Con: 41 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, HeLa cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
nucleoredoxin-like 1

Calculated molecular weight:
24 kDa

Observed molecular weight:
26-28kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NXNL1

Synonyms
nucleoredoxin like 1, Nucleoredoxin like protein 1, NXNL1, RDCVF, Thioredoxin like protein 6, TXNL6
Background

TXNL6, also named as NXNL1, belongs to the nucleoredoxin family. It may play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods. TXNL6 is a Novel Oxidative Stress-Induced Reducing System for Methionine Sulfoxide Reductase A Repair of a-Crystallin and Cytochrome C in the Eye Lens. It serve as a reducing system for MsrA repair of the essential lens chaperone a-crystallin/sHSP and mitochondrial cytochrome c. TXNL6 is induced at high levels in human lens epithelial cells exposed to H2O2-induced oxidative stress.(PMID:21079812)


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