OLR1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 11837-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 69 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human liver tissue

Positive IP detected in:
L02 cells

Positive IHC detected in:
human heart tissue

Positive FC detected in:
HUVEC cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
oxidized low density lipoprotein (lectin-like) receptor 1

Calculated molecular weight:
273aa,31 kDa

Observed molecular weight:
48-52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OLR1

Synonyms
CLEC8A, hLOX 1, Lectin like oxLDL receptor 1, LOX 1, LOX1, OLR1, Ox LDL receptor 1, SCARE1
Background

OLR1/LOX-1 acts as a receptor, in the form of homodimer, that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) (PMID: 9052782, 15695803). ORL1 is predominantly expressed in endothelial cells and vascular-rich organs such as placenta, lung, liver and brain (PMID: 9828121). OLR1 is a protein containing 273 amino acid with the calculated molecular mass of 31 kDa but an apparent molecular mass of 50 kDa, which may result from glycosylation of four potential N-linked glycosylation sites located at C-terminal domain (PMID: 9052782).


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