PCK1 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 16754-1-AP

Featured Product KD/KO validated

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Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat, pig

Positive WB detected in:
HepG2 cells

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphoenolpyruvate carboxykinase 1 (soluble)

Calculated molecular weight:
622aa,69 kDa

Observed molecular weight:
67 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PCK1

Synonyms
PCK1, PEPCK C, PEPCK1, PEPCKC, Phosphoenolpyruvate carboxykinase 1
Background

PCK1(Phosphoenolpyruvate carboxykinase, cytosolic) is also named as PEPCK1 and belongs to the phosphoenolpyruvate carboxykinase [GTP] family. It catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. It is also a main control point for the regulation of gluconeogenesis. In eukaryotes there are two isozymes: a cytoplasmic one and a mitochondrial one. Defects in PCK1 are the cause of cytosolic phosphoenolpyruvate carboxykinase deficiency (C-PEPCKD).


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