PD-L2/CD273 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18251-1-AP

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Freight/Packing

Con: 29 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
RAW 264.7 cells, HepG2 cells

Positive IHC detected in:
human tonsillitis tissue, human skin tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
programmed cell death 1 ligand 2

Calculated molecular weight:
273aa,31 kDa

Observed molecular weight:
28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PDCD1LG2

Synonyms
B7 DC, bA574F11.2, Btdc, Butyrophilin B7 DC, CD273, PD 1 ligand 2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, PD-L2, Programmed death ligand 2
Background

Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery. Mouse PD-L2 has a predicted molecular weight of 28 kDa.


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