PGAM1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 16126-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, A549 cells, HepG2 cells, human brain tissue, L02 cells, MCF-7 cells, mouse liver tissue, rat brain tissue, rat liver tissue

Positive IHC detected in:
human brain tissue

Positive IF detected in:
A549 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphoglycerate mutase 1 (brain)

Calculated molecular weight:
254aa,29 kDa

Observed molecular weight:
29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PGAM1

Synonyms
BPG dependent PGAM 1, PGAM B, PGAM1, PGAMA, Phosphoglycerate mutase 1
Background

PGAM1(phosphoglycerate mutase 1) is also named as PGAMA,PGAM-B and belongs to the phosphoglycerate mutase family. Phosphoglycerate mutase is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The homodimer PGAM1 is expressed mainly in liver, kidney, brain and overexpressed in a variety of human cancers, including breast carcinoma, colorectal cancer, lung cancer, prostate cancer, oral squamous cell carcinoma, esophageal squamous cell carcinomas and also associated with certain virus infection. PGAM1 could be developed as a useful diagnostic biomarker, as well as a potential therapeutic target for hepatocellular carcinoma.(PMID:20403181). This antibody is specific to PGAM1.


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