PI4KA Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12411-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, NIH-3T3 cells (RNAi)

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human breast cancer tissue, human placenta tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphatidylinositol 4-kinase, catalytic, alpha

Calculated molecular weight:
2044aa,231 kDa

Observed molecular weight:
231 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PI4KA

Synonyms
FLJ16556, PI4 kinase alpha, PI4K ALPHA, pi4K230, PI4KA, PIK4, PIK4CA, PtdIns 4 kinase alpha
Background

PI4KA, also named as PIK4, PIK4CA, belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. It acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate. PI4KA plays a role in the formation of membrane complexes where HCV replication takes place. (PMID:19605471).


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