PLK4 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 12952-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse lung tissue, A549 cells, MCF-7 cells, mouse lung tissue

Positive IHC detected in:
human testis tissue, human cervical cancer tissue, human lung cancer tissue, human testis tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:100-1:400
IF : 1:25-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
polo-like kinase 4 (Drosophila)

Calculated molecular weight:
970aa,109 kDa

Observed molecular weight:
105-112 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PLK4

Synonyms
PLK 4, PLK4, Polo like kinase 4, SAK, STK18
Background

PLK4(Polo-like kinase 4) is also named as SAK, STK18 and belongs to the Ser/Thr protein kinase family.It plays a central role in centriole duplication and a kinase implicated in tumor development, which is an upstream regulator of canonical biogenesis necessary for centriole formation.It has 3 isoforms produced by alternative splicing.


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