PPBP,NAP2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13313-1-AP

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Con: 31 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse liver tissue, human liver tissue, human plasma tissue

Positive IHC detected in:
human placenta tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

Calculated molecular weight:
128aa,14 kDa

Observed molecular weight:
8-14 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PPBP

Synonyms
B TG1, Beta TG, C X C motif chemokine 7, CTAP III, CTAP3, CTAPIII, CXCL7, LA PF4, LDGF, MDGF, NAP 2, NAP 2(1 63), NAP-2, PBP, Platelet basic protein, PPBP, SCYB7, Small inducible cytokine B7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
Background

PPBP, slso named as NAP2, or β-Thromboglobulin, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.


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