PSMB5 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 19178-1-AP

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Freight/Packing

Con: 33 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
L02 cells, HeLa cells, Jurkat cells, L02 cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human hepatocirrhosis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
proteasome (prosome, macropain) subunit, beta type, 5

Calculated molecular weight:
263aa,28 kDa

Observed molecular weight:
22kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PSMB5

Synonyms
20S proteasome, LMPX, Macropain epsilon chain, MB1, Proteasome chain 6, Proteasome epsilon chain, Proteasome subunit beta type 5, Proteasome subunit MB1, Proteasome subunit X, PSMB5, X
Background

PSMB5(Proteasome subunit beta type-5) is also named as LMPX, MB1, X and belongs to the peptidase T1B family.The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.RNAi-mediated silencing of PSMB5 expression resulted in restoration of bortezomib sensitivity in resistant cells(PMID:18565852).It has 2 isoforms produced by alternative splicing.


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