RAB11-Specific Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 20229-1-AP

Featured Product KD/KO validated

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Con: 38 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, human brain tissue, mouse colon tissue, SH-SY5Y cells

Positive IP detected in:
SH-SY5Y cells

Positive IF detected in:
IMCD3 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
RAB11A, member RAS oncogene family

Calculated molecular weight:
24 kDa

Observed molecular weight:
24 kDa, 29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RAB11A

Synonyms
Rab 11, RAB11, RAB11A, Ras related protein Rab 11A, YL8
Background

Rab11a, Rab11b and Rab25 comprise a subfamily of Rab proteins that belong to the Ras-related small GTPase protein superfamily (PMID: 8074219, PMID: 10708602). Rab11 proteins are involved in endocytosis and plasma membrane recycling in non-polarized and polarized cells ( PMID: 8638719, PMID: 8922376). Rab11a and Rab11b are ubiquitously expressed in most tissues, while Rab25 is only expressed in epithelial cells. Rab11a is known to regulate the recycling of internalized cell surface proteins and receptors from the early endosome through the trans-Golgi network (PMID: 11121436, PMID: 9600939). The antibody is specific to RAB11A, and has no cross reaction to RAB11B.


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