RAF1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 26863-1-AP

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Freight/Packing

Con: 100 μg/150 μl

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Species specificity:
human

Positive WB detected in:
DU 145 cells

Positive IHC detected in:
human prostate cancer tissue, human colon cancer tissue, human prostate cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-raf-1 murine leukemia viral oncogene homolog 1

Calculated molecular weight:
648aa,73 kDa

Observed molecular weight:
76 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RAF1

Synonyms
c Raf, CRAF, NS5, Proto oncogene c RAF, RAF, Raf 1, RAF1
Background

Raf-1 proto-oncogene, serine/threonine kinase(RAF1), is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. RAF1 has two isoforms with MW of 73, 75 kDa. RAF1 plays an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.


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