RBM3 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 14363-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 53 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A375 cells, MCF-7 cells, Raji cells, HepG2 cells

Positive IP detected in:
MCF-7 cells

Positive IHC detected in:
human testis tissue, human lung tissue, human brain tissue, human kidney tissue, human spleen tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
RNA binding motif (RNP1, RRM) protein 3

Calculated molecular weight:
17 kDa

Observed molecular weight:
17-20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RBM3

Synonyms
IS1 RNPL, Putative RNA binding protein 3, RBM3, RNA binding motif protein 3, RNPL
Background

RBM3, also named as RNPL, is a cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. It reduces the relative abundance of microRNAs, when overexpressed. RBM3 enhances phosphoryaltion of translation initiation factors and active polysome formation. It is up-regulated in human tumors. RBM3 is a potential proto-oncogenic proteins upon overexpression. (PMID: 19900510 ).


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