RCC1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22335-1-AP

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Freight/Packing

Con: 40 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HepG2 cells, SH-SY5Y cells, mouse colon tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human testis tissue, human small intestine tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:3000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
regulator of chromosome condensation 1

Calculated molecular weight:
421aa,45 kDa

Observed molecular weight:
45-50 kDa,68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RCC1

Synonyms
Cell cycle regulatory protein, CHC1, RCC1, RCC1 I
Background

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against full length RCC1 of human origin.


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