RQCD1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 22503-1-AP

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Freight/Packing

Con: 55 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse thymus tissue, HepG2 cells, MCF-7 cells

Positive IP detected in:
MCF-7 cells

Positive IHC detected in:
human small intestine tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
RCD1 required for cell differentiation1 homolog (S. pombe)

Calculated molecular weight:
299aa,34 kDa

Observed molecular weight:
34-40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RQCD1

Synonyms
CNOT9, Rcd 1, RCD1, RCD1+, RQCD1
Background

RQCD1, also known as CNOT9, is a highly conserved transcriptional cofactor predominantly expressed in actively diffierentiating tissues like testis and thymus. It is a component of the CCR4-NOT complex, the major effector complex in miRNA-mediated gene silencing. Overexpression of RQCD1 has been reported in serveral tumors, indicating that it may be a potential molecular target for cancer treatment.


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