- Featured Product
- KD/KO Validated
RSPO2 Polyclonal Antibody for IHC, IP, WB, ELISA
Cat no : 17781-1-AP
CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2
|Positive WB detected in||mouse brain tissue|
|Positive IP detected in||mouse brain tissue|
|Positive IHC detected in||mouse small intestine tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:200-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
17781-1-AP targets RSPO2 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||RSPO2 fusion protein Ag11216|
|Full Name||R-spondin 2 homolog (Xenopus laevis)|
|Calculated molecular weight||243aa,28 kDa|
|Observed molecular weight||33 kDa|
|GenBank accession number||BC027938|
|Gene ID (NCBI)||340419|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.
BMC Res Notes
R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.
Mol Biol Rep
RSPO fusion transcripts in colorectal cancer in Japanese population.
DNA Cell Biol
Expression and Prognostic Values of the Roof Plate-Specific Spondin Family in Bladder Cancer.