|Positive WB detected in||T-47D cells, A431 cells, BxPC-3 cells, DU 145 cells|
|Positive IHC detected in||human lung cancer tissue, human ovary tumor tissue, human thyroid cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:1000-1:3000|
|Immunohistochemistry (IHC)||IHC : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
60024-1-Ig targets S100A11 in WB, IHC, ELISA applications and shows reactivity with human samples.
|Host / Isotype||Mouse / IgG1|
|Immunogen||S100A11 fusion protein Ag0343|
|Full Name||S100 calcium binding protein A11|
|Calculated molecular weight||105 aa, 12 kDa|
|Observed molecular weight||12 kDa|
|GenBank accession number||BC001410|
|Gene ID (NCBI)||6282|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
S100A11, also named as MLN 70, Calgizzarin and S100C, belongs to the S-100 family. It facilitates the differentiation and the cornification of keratinocytes. The naming of S100A11 systematically arises from its membership of the S100 protein family, named after their solubility in 100% saturated ammonium sulfate solution. First discovered in 1989, S100A11 has since been proposed to have direct biological functions in an assortment of physiological processes such as endo- and exocytosis, regulation of enzyme activity, cell growth and regulation, apoptosis and inflammation.
Proteomic analysis of the triglyceride-rich lipoprotein-laden foam cells.
Effective enrichment of cholangiocarcinoma secretomes using the hollow fiber bioreactor culture system.
Mol Cell Proteomics
S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation.