SALL4 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 24500-1-AP

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Con: 56 μg/150 μl

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Species specificity:
human, rat

Positive WB detected in:
HepG2 cells, rat liver tissue

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human testis tissue, human ovary tumor tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
sal-like 4 (Drosophila)

Calculated molecular weight:
1053aa,112 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol

DRRS, HSAL4, sal like 4 (Drosophila), Sal like protein 4, SALL4, Zinc finger protein SALL4, ZNF797

SALL4, also named as Sal-like protein 4 or Zinc finger protein 797, Contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is constitutively expressed in acute myeloid leukemia. The constitutive expression of SALL4in mice is sufficient to induce MDS-like symptoms and transformation to AML that is transplantable. SALL4 is able to bind beta-catenin and activate the Wnt/beta catenin signaling pathway. Sequence analysis of the larger cDNA fragment isolated revealed a single, large open-reading frame, designated as SALL4A, that started from a strong consensus initiation sequence and was expected to encode 1053 amino acids. The other splicing variant of SALL4, designated SALL4B, lacked the region corresponding to amino acids 385 to 820 of the full-length SALL4A. The putative protein encoded by SALL4B cDNA was expected to consist of 617 amino acids.

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