SDHC Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14575-1-AP

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Freight/Packing

Con: 53 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human liver tissue, HepG2 cells, MCF-7 cells, mouse lung tissue

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa

Calculated molecular weight:
19 kDa

Observed molecular weight:
15kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SDHC

Synonyms
CYB560, CYBL, PGL3, QPs 1, QPS1, SDH3, SDHC
Background

SDHC(Succinate dehydrogenase cytochrome b560 subunit, mitochondrial) is also named as CYB560, SDH3 and belongs to the cytochrome b560 family. It is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Defects in SDHC are the cause of paragangliomas type 3 (PGL3) and paraganglioma and gastric stromal sarcoma (PGGSS). It has a transit peptide of 29 amino acid and has 5 isoforms produced by alternative splicing.


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