GLUT3 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 20403-1-AP

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Con: 49 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, HEK-293 cells, HeLa cells, HepG2 cells

Positive IHC detected in:
human brain tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
solute carrier family 2 (facilitated glucose transporter), member 3

Calculated molecular weight:
496aa,54 kDa

Observed molecular weight:
48kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SLC2A3

Synonyms
GLUT 3, GLUT3, SLC2A3
Background

GLUT3 (SLC2A3) belongs to the glucose transporter family (GLUTs) which mediates the transport of glucose across cellular membranes in mammalian cells. There are three subclasses within GLUTs: class I comprises the classical transporters GLUT1-4 and GLUT14; class II contains the "odd" isoforms GLUT5, 7, 9, and 11; the isoforms GLUT6, 8, 10, 12 and the proton driven myoinositol transporter HMIT (GLUT13) belong to class III. GLUT3 is considered as a neuron-specific glucose transporter because of its dominant expression in the brain in various species. However, besides the brain GLUT3 is also expressed in tissues with high demand for glucose such as sperm, preimplantation embryos, circulating white blood cells, and an array of carcinoma cell lines.Recently GLUT3 has been identified as a sensitive and specific marker for embyonal carcinomas and yolk tumors.The GLUT14 is believed to be the duplicate gene of GLUT3 given to the high identity in sequence between them. This antibody was generated against the internal region of human GLUT3 and may cross-react with GLUT14. (23343953)


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