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GLUT3 Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 20403-1-AP

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Con: 49 μg/150 μl

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Tested Applications

Applications:
WB, IHC, ELISA
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Images See all

GLUT3 Antibody WB HepG2 cells 20403-1-AP

HepG2 cells were subjected to SDS PAGE followed by western blot with 20403-1-AP( GLUT3 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours

GLUT3 Antibody IHC human lung cancer tissue 20403-1-AP

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 20403-1-AP( GLUT3 antibody at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

GLUT3 Antibody IHC human lung cancer tissue 20403-1-AP

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 20403-1-AP( GLUT3 antibody at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Species specificity:
human, mouse
Positive WB detected in:
HepG2 cells, Jurkat cells, mouse brain tissue, HeLa cells, HEK-293 cells
Positive IHC detected in:
human lung cancer tissue, human brain tissue
Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
GLUT3 fusion protein Ag14203
Full name:
solute carrier family 2 (facilitated glucose transporter), member 3
Calculated molecular weight:
496aa,54 kDa
Observed molecular weight:
48-60 kDa
GenBank accession number:
BC039196
Gene ID (NCBI):
6515
Gene symbol
SLC2A3
Synonyms
GLUT 3, GLUT3, SLC2A3

Background

GLUT3 (SLC2A3) belongs to the glucose transporter family (GLUTs) which mediates the transport of glucose across cellular membranes in mammalian cells. There are three subclasses within GLUTs: class I comprises the classical transporters GLUT1-4 and GLUT14; class II contains the "odd" isoforms GLUT5, 7, 9, and 11; the isoforms GLUT6, 8, 10, 12 and the proton driven myoinositol transporter HMIT (GLUT13) belong to class III. GLUT3 is considered as a neuron-specific glucose transporter because of its dominant expression in the brain in various species. However, besides the brain GLUT3 is also expressed in tissues with high demand for glucose such as sperm, preimplantation embryos, circulating white blood cells, and an array of carcinoma cell lines.Recently GLUT3 has been identified as a sensitive and specific marker for embyonal carcinomas and yolk tumors.The GLUT14 is believed to be the duplicate gene of GLUT3 given to the high identity in sequence between them. This antibody was generated against the internal region of human GLUT3 and may cross-react with GLUT14. 20403-1-AP antibody detects the bands around 48-60 kDa in SDS-PAGE. (23343953; 23866118; 28574837)


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