CD98 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 15193-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 52 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells, A375 cells, Raji cells

Positive IHC detected in:
human testis tissue, human placenta tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:2500-1:10000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Calculated molecular weight:
68 kDa

Observed molecular weight:
85 kDa,120 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SLC3A2

Synonyms
4F2, 4F2 heavy chain antigen, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE, SLC3A2
Background

CD98 is a cell-surface heterodimer consisting of a heavy chain (CD98hc) and a light chain. CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.(PMID:25084765). This protein has 4 isoforms produced by alternative splicing.


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