BAF170 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12018-1-AP

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Freight/Packing

Con: 111 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A431 cells, HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human medulloblastoma tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Calculated molecular weight:
1214aa,132 kDa

Observed molecular weight:
170 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SMARCC2

Synonyms
BAF170, BRG1 associated factor 170, CRACC2, Rsc8, SMARCC2
Background

BAF170, also named as SWI/SNF complex 170 kDa subunit or SMARCC2, is a 1214 amino acid protein, which belongs to the SMARCC family. BAF170 is ubiquitously expressed. BAF170 is involved in transcriptional activation and repression of select genes by chromatin remodeling. BAF170 may be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. BAF170 belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). The calcualted molecular weight of BAF170, is 133 kDa, but modified BAF170 is about 170 kDa. (PMID: 8804307)


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