SNCAIP Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17818-1-AP

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Freight/Packing

Con: 56 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, fetal human brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human kidney tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
synuclein, alpha interacting protein

Calculated molecular weight:
603aa,67 kDa;1016aa,111 kDa

Observed molecular weight:
100, 75 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SNCAIP

Synonyms
SNCAIP, Sph1, Synphilin 1, SYPH1
Background

SNCAIP, also named as Synphilin-1 or Alpha-synuclein-interacting protein, is a 919 amino acid protein, which contains six ANK repeats. SNCAIP is detected in brain and is widely expressed, with highest levels in brain, heart and placenta. SNCAIP localizes in the cytoplasm and inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. SNCAIP has an association with Parkinson disease.


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