TEAD4 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12418-1-AP

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Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
MDA-MB-453s cells, BGC-823 cells, MCF-7 cells

Positive IP detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
TEA domain family member 4

Calculated molecular weight:
434aa,48 kDa

Observed molecular weight:
65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TEAD4

Synonyms
EFTR 2, hRTEF 1B, RTEF1, TCF13L1, TEA domain family member 4, TEAD 4, TEAD4, TEF 3, TEF3, TEFR 1, Transcription factor 13 like 1, Transcription factor RTEF 1
Background

TEAD4 belongs to a protein family that share the TEA/ATTS domain. The transcriptional activity of TEAD4 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary facotrs. TEAD4 also preforms an essential role in the Hippo signaling pathway. TEAD4 regulates gene rexpression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. The calcualted molecular weight of TEAD4 is 48 kDa, but molecular weight of TEAD4 is detected about 65 kDa as same as the result from the paper (PMID: 28051067).


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