TFPT Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10097-2-AP

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Freight/Packing

Con: 63 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
K-562 cells, HL-60 cells, mouse liver tissue, PC-3 cells

Positive IHC detected in:
human tonsillitis tissue, human brain tissue, human liver tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
TCF3 (E2A) fusion partner (in childhood Leukemia)

Calculated molecular weight:
29 kDa

Observed molecular weight:
29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TFPT

Synonyms
amida, FB1, INO80 complex subunit F, INO80F, Protein FB1, TCF3 fusion partner, TFPT
Background

TFPT/FB1 is one of three fusion partners of the E2A gene. TFPT/FB1 is expressed at low level in a variety of human tissues, including hemopoietic cell lines from different lineages. The function of the putative TFPT/FB1 protein, however, is currently unknown as database sequence comparisons have failed to reveal strong homology with known proteins. The E2A-TFPT/FB1 fusion appears to be a recurrent feature of pre-B ALLs, suggesting that it might have a role in the development and/or progression of leukemogenesis. The gene encoding TFPT/FB1 is localized on 19q13.4.


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