Transferrin receptor/CD71 Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 10084-2-AP

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Freight/Packing

Con: 28 μg/150 μl

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Species specificity:
human, mouse, rat, monkey, pig

Positive WB detected in:
MCF7 cells, HeLa cells, K-562 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human placenta tissue, human lymphoma tissue, human placenta tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
transferrin receptor (p90, CD71)

Calculated molecular weight:
85 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TFRC

Synonyms
CD71, p90, sTfR, T9, TFR, TFR1, TFRC, TR, Transferrin receptor, Transferrin receptor protein 1, TRFR
Background

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.


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