THOC5 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14862-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 31 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, HeLa cells, NIH/3T3 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human breast cancer tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HEK-293 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
THO complex 5

Calculated molecular weight:
79 kDa

Observed molecular weight:
79 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
THOC5

Synonyms
C22orf19, Fmip, fSAP79, hTREX90, KIAA0983, PK1.3, Placental protein 39.2, PP39.2, THO complex 5, THO complex subunit 5 homolog, THOC5
Background

THOC5, also named as C22orf19, or KIAA0983, is a 683 amino acid protein, which belongs to the THOC5 family. THOC5 is ubiquitously expressed in many tissues. THOC5 localizes in the nucleus and acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.THOC5 plays a role in cytokine-stimulated monocytic development and affects granulocyte/macrophage differentiation.


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