TIMM13 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 11973-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human

Positive WB detected in:
PC-3 cells

Positive IHC detected in:
human liver tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
translocase of inner mitochondrial membrane 13 homolog (yeast)

Calculated molecular weight:
95aa,11 kDa

Observed molecular weight:
11 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TIMM13

Synonyms
ppv1, TIM13, TIM13B, TIMM13, TIMM13A, TIMM13B
Background

TIMM13 gene, also known as TIM13, TIM13B, TIM M13A or TIMM13B, encodes mitochondrial import inner membrane translocase subunit Tim13 belonging to the small Tim family. TIM13 functions as mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Proteins of the intermembrane space (IMS) of mitochondria are typically synthesized without presequences. TIM13 contains four conserved cysteine residues that bind a zinc ion as cofactor. Import of TIM13 did not depend on the membrane potential or ATP hydrolysis. Upon import into mitochondria TIM13 adopted a stably folded conformation in the IMS.


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