TMS1 Antibody 20 Publications

Rabbit Polyclonal| Catalog number: 10500-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, cow

Positive WB detected in:
HL-60 cells,Raji cells, U-937 cells, A549 cells

Positive IP detected in:
HL-60 cells

Positive IHC detected in:
human lung cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
PYD and CARD domain containing

Calculated molecular weight:
25 kDa

Observed molecular weight:
22-25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PYCARD

Synonyms
ASC, CARD5, hASC, PYCARD, PYD and CARD domain containing, TMS, TMS 1, TMS1
Background

PYCARD , also known as ASC or TMS1, is a 195 amino acid protein containing an N-terminal Pyrin-like domain (PYD) and an 87 residue C-terminal Caspase-associated recruitment domain (CARD). It promotes caspase-mediated apoptosis which is mediated predominantly through the activation of caspase-9.


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