|Positive WB detected in||mouse testis tissue, human liver tissue|
|Positive IHC detected in||human gliomas tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
11511-1-AP targets TRIM44 in WB, IHC,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||TRIM44 fusion protein Ag2070|
|Full Name||tripartite motif-containing 44|
|Calculated molecular weight||344 aa, 38 kDa|
|Observed molecular weight||50-55 kDa|
|GenBank accession number||BC024031|
|Gene ID (NCBI)||54765|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
TRIM44 is one of the family member of TRIM protein, which contains an N-terminal ubiquitin hydrolase-type zinc-finger domain, followed by a coiled-coil domain, a zinc-finger B-box homology domain, and a second coiled-coil domain near the C-terminus. Members of the TRIM protein family are involved in various cellular processes, such as cell proliferation, oncogenesis and antiviral defense. This is a rabbit polyantibody raised against full length of human TRIM44.
Int J Clin Oncol
Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.
TRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway.
Onco Targets Ther
TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma.
Onco Targets Ther
TRIM44 Promotes Colorectal Cancer Proliferation, Migration, and Invasion Through the Akt/mTOR Signaling Pathway.
TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway.