TRPV1-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19735-1-AP

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Freight/Packing

Con: 21 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
transient receptor potential cation channel, subfamily V, member 1

Calculated molecular weight:
95 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TRPV1

Synonyms
Capsaicin receptor, DKFZp434K0220, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1
Background

TRPV1, also named as OTRPC1 and VR1, belongs to the transient receptor family and TrpV subfamily. TRPV1 is a receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. It seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. TRPV1 may be involved in mediation of inflammatory pain and hyperalgesia. It is sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. This antibody is specific to TRPV1.


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