TRPV6 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 13411-1-AP

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Freight/Packing

Con: 73 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human placenta tissue, mouse kidney tissue, PC-3 cells

Positive IP detected in:
mouse kidney tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
transient receptor potential cation channel, subfamily V, member 6

Calculated molecular weight:
725aa,83 kDa

Observed molecular weight:
83 kDa, 70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TRPV6

Synonyms
ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB
Background

TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.


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