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Thrombospondin 1 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 18304-1-AP

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Con: 30 μg/150 μl

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Tested Applications

Applications:
WB, IHC, IF, ELISA
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Images See all

Thrombospondin 1 Antibody WB C6 cells 18304-1-AP

Various lysates were subjected to SDS PAGE followed by western blot with 18304-1-AP (Thrombospondin 1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

Thrombospondin 1 Antibody IHC human lung cancer tissue 18304-1-AP

Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 18304-1-AP (Thrombospondin 1 antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Thrombospondin 1 Antibody IHC human lung cancer tissue 18304-1-AP

Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 18304-1-AP (Thrombospondin 1 antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Species specificity:
human, rat, mouse
Positive WB detected in:
C6 cells, Human peripheral blood platelets tissue, A431 cells, HeLa cells, NIH/3T3 cells
Positive IHC detected in:
human lung cancer tissue, human placenta tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Peptide
Full name:
thrombospondin 1
Calculated molecular weight:
129 kDa
Observed molecular weight:
180 kDa
GenBank accession number:
BC028145
Gene ID (NCBI):
7057
Gene symbol
THBS1
Synonyms
THBS, THBS 1, THBS1, thrombospondin 1, TSP, TSP 1, TSP1

Background

TSP1, also named as THBS1, THBS and TSP, is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions, and which can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3. TSP1 is a regulator of many biological processes including cell growth, adhesion, migration, platelet aggregation, and fibrin deposition and lysis. It interacts with a number of plasma proteins such as fibrinogen and plasminogen and co-polymerizes with fibrin in clot formation. Secreted TSP1 is a glycoprotein with a molecular mass of 150-180 kDa.


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