Thrombospondin 1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 18304-1-AP

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Freight/Packing

Con: 67 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
HeLa cells, A431 cells, A549 cells, C6 cells, HeLa cells, human heart tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human gliomas tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
thrombospondin 1

Calculated molecular weight:
129 kDa

Observed molecular weight:
165-198 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
THBS1

Synonyms
THBS, THBS 1, THBS1, thrombospondin 1, TSP, TSP 1, TSP1
Background

TSP1, also named as THBS1, THBS and TSP, is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions, and which can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3. TSP1 is a regulator of many biological processes including cell growth, adhesion, migration, platelet aggregation, and fibrin deposition and lysis. It interacts with a number of plasma proteins such as fibrinogen and plasminogen and co-polymerizes with fibrin in clot formation. TSP1 is a 420 kDa homotrimeric glycoprotein with disulfide-linked subunits of 180 kDa.


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