TWIST1 Antibody

TWIST1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 18125-1-AP

Synonyms

ACS3, bHLHa38, BPES2, BPES3, H twist, SCS, TWIST, twist homolog 1 (Drosophila), Twist related protein 1, TWIST1



Tested Applications

Positive WB detected inPC-3 cells, MCF-7 cells, SGC-7901 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Sample-dependent, check data in validation data gallery

Product Information

The 18125-1-AP immunogen is Fusion Protein TWIST1 protein expressed in E. coli.

Tested Reactivity human
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TWIST1 fusion protein Ag12700
Full Name twist homolog 1 (Drosophila)
Calculated molecular weight 202aa,21 kDa
Observed molecular weight 22, 28, 45-60 kDa
GenBank accession number BC036704
Gene symbol TWIST1
Gene ID (NCBI) 7291
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TWIST1, a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. It is also implicated in tumorigenesis, invasion and metastasis. TWIST1 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).

Publications

SpeciesApplicationTitle
humanWB

J Cell Mol Med

SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.

Authors - Wei Wu
humanWB

Int J Biochem Cell Biol

Blue light emitting diodes irradiation causes cell death in colorectal cancer by inducing ROS production and DNA damage.

Authors - Gege Yan
WB

Acta Biochim Biophys Sin (Shanghai)

STK33 plays an important positive role in the development of human large cell lung cancers with variable metastatic potential.

Authors - Ping Wang
humanWB

Dig Dis Sci

HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer.

Authors - Zha Lang L
ratWB

Biomed Pharmacother

Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.

Authors - Wang Huijuan
humanWB

Biomed Pharmacother

Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.

Authors - Bin Zhao