TXNL1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 15289-1-AP

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Freight/Packing

Con: 63 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
K-562 cells, HL-60 cells

Positive IP detected in:
HL-60 cells

Positive IHC detected in:
human heart tissue, human thyroid cancer tissue

Positive IF detected in:
RAW 264.7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
thioredoxin-like 1

Calculated molecular weight:
32 kDa

Observed molecular weight:
32 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TXNL1

Synonyms
thioredoxin like 1, Thioredoxin like protein 1, TRP32, Txl, TXL 1, TXNL, TXNL1
Background

TXNL1(Thioredoxin-like protein 1) is also named as TRP32, TXL, TXNL and belongs to the thioredoxin family. It might be involved in the cellular response to sugar starvation stress. The predicted 289-amino acid, 32.3-kD protein has 2 distinct domains: an N-terminal domain, which is 43% identical to human TXN, and a C-terminal domain, which showed no homology to other proteins in the sequence databases(PMID:9473519).TXNL1 functions as an effector of oxidants or redox sensor that couples oxidative stress to endocytosis, by converting redox changes into a specific GDI:Rab5-mediated endocytic response(PMID:17987124).


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