UGCG Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12869-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 46 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, C6 cells, mouse brain tissue, U-251 cells

Positive IP detected in:
A375 cells

Positive IHC detected in:
human lung cancer tissue, human breast cancer tissue, human lymphoma tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
UDP-glucose ceramide glucosyltransferase

Calculated molecular weight:
394aa,45 kDa

Observed molecular weight:
50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
UGCG

Synonyms
Ceramide glucosyltransferase, GCS, GLCT 1, Glucosylceramide synthase, UGCG
Background

UGCG, also named as GCS and GLCT-1, belongs to the glycosyltransferase 2 family. It catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. UGCG may also serve as a "flippase". It is up-regulated at the transcriptional level during keratinocyte differentiation. UGCG is a membrane protein. The calculated MW is 45kd. In SDS-PAGE, it is about 50-55kd.


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