Phospho-Akt (Tyr315) Antibody 11 Publications

Mouse Monoclonal| Catalog number: 60072-1-Ig |CloneNo.: 5C4D12

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 112 μg/150 μl

Choose size:

Please visit your regions distributor:

Tested Applications

Applications:
ELISA, WB, IF
Application not tested? Please see our Guarantee




Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Phospho Peptide

Full name:
v-akt murine thymoma viral oncogene homolog 1

Calculated molecular weight:
56 kDa

Observed molecular weight:
62 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AKT1

Synonyms
Background

Protein kinase B (PKB/Akt) has been well established as an important signaling intermediate, and its deregulation has been implicated in the development of human cancer and diabetes(PMID:12176337). Akt, also known as protein kinase B (PKB), is a serine/threonine kinase activated downstream of class I phosphatidylinositol 3-kinase (PI3K) and various receptors. It has emerged as the key regulator for many signal transduction pathways, modulating multiple processes such as cell survival, proliferation, growth, angiogenesis, and glucose metabolism(PMID:16139227). Its deregulation has been implicated in the development of human cancer and diabetes(PMID:12176337).


Back
to top