Validation Data Gallery
Technical Specifications
| GeneID | 10637 |
| Species | Human |
| Expression | HEK293 |
| Activity(Primary) | Typically ≤ 2.5 µg/mL |
| Purity | >95% |
| Endotoxin | <1 EU/μg |
| Accession Number | O75610 |
| Molecular Mass | 43 kDa reduced, 40 and 43 kDa non-reduced, monomer, glycosylated |
| Formulation | 10 mM Tris pH 7.4 + 450 mM NaCl + 1% CHAPS, See Certificate of Analysis for details |
| Species Reactivity | human,mouse |
Stability and Reconstitution
| Stability and Storage | Product Form | Temperature Conditions | Storage Time (From Date of Receipt) |
|---|---|---|---|
| Lyophilized | -20°C to -80°C | Until Expiry Date | |
| Lyophilized | Room Temperature | 2 weeks | |
| Reconstituted as per CofA | -20°C to -80°C | 6 months | |
| Reconstituted as per CofA | 4°C | 1 week | |
| Avoid repeated freeze-thaw cycles. | |||
| Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix. |
Background
LEFTY-1 is a member of the TGF-beta family of proteins that plays a role in left-right asymmetry determination of organ systems during development. LEFTY-1 regulates transforming growth factor, mitogen-activated protein kinase and other signaling pathways, and is considered to have a potential anti-inflammatory function (PMID: 29286065; 26316705; 10500184; 9708731)
Synonyms
LEFTB, LEFTY1, LEFTYB, Protein lefty 1, Protein lefty B
Publications
| Species | Title |
|---|---|
Stem Cells Dev Lefty Glycoproteins in Human Embryonic Stem Cells: Extracellular Delivery Route and Posttranslational Modification in Differentiation. |
