CD38 Monoklonaler Antikörper
CD38 Monoklonal Antikörper für IF/ICC, FC
Wirt / Isotyp
Ratte / IgG2a, kappa
Getestete Reaktivität
Maus
Anwendung
IF/ICC, FC
Konjugation
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
90
Kat-Nr. : CL647-65059
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in IF/ICC | Maus-Splenozyten |
Erfolgreiche Detektion in FC | Maus-Splenozyten |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
Immunfluoreszenz (IF)/ICC | IF/ICC : 1:200-1:800 |
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
CL647-65059 bindet in IF/ICC, FC CD38 und zeigt Reaktivität mit Maus
Getestete Reaktivität | Maus |
Wirt / Isotyp | Ratte / IgG2a, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Maus-Knochenmark-Vorläufer-B-Zellen |
Vollständiger Name | CD38 antigen |
GenBank-Zugangsnummer | BC046312 |
Gene symbol | Cd38 |
Gene ID (NCBI) | 12494 |
Konjugation | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 654 nm / 674 nm |
Form | Liquid |
Reinigungsmethode | Affinitätsreinigung |
Lagerungspuffer | PBS with 0.09% sodium azide and 0.5% BSA |
Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Hintergrundinformationen
CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
---|---|
IF protocol for CL Plus 647 CD38 antibody CL647-65059 | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
---|---|
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |