CD45.1 Monoklonaler Antikörper

CD45.1 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

A20

Kat-Nr. : 65092-1-Ig

Synonyme

B220, CD45.1, CD45R, loc, Ly 5, Lyt 4, Ptprc, T200



Geprüfte Anwendungen

Erfolgreiche Detektion in FCSJL-Maus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65092-1-Ig bindet in FC CD45.1 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen SJL-Maus-Thymozyten und -Splenozyten
Vollständiger Name protein tyrosine phosphatase, receptor type, C
GenBank-ZugangsnummerBC028512
Gene symbol Ptprc
Gene ID (NCBI) 19264
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer Phosphatbasierter Puffer mit 0,09% Natriumazid, pH 7,2.
LagerungsbedingungenBei 2-8℃ lagern.

Hintergrundinformationen

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). Allelic variants of mouse CD45, CD45.1 (Ly5.1) and CD45.2 (Ly5.1), have been established as a marker system to track haematopoietic cells following congenic mouse bone marrow transplants (PMID: 28615666). CD45.2 is the common form and is expressed by most of the established strains, while CD45.1 is found in only a few like the SJL mouse strain (PMID: 3489673).

Protokolle

Produktspezifische Protokolle
FC protocol for CD45.1 antibody 65092-1-IgProtokoll herunterladen
Standard-Protokolle
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