CD62L Monoklonaler Antikörper

CD62L Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / Mouse IgG1

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

DREG56

Kat-Nr. : 65167-1-Ig

Synonyme

CD62L, gp90 MEL, hLHRc, L selectin, LAM 1, LAM1, LECAM1, Leu 8, Leukocyte adhesion molecule 1, LNHR, LSEL, Lyam 1, LYAM1, Lymph node homing receptor, PLNHR, selectin L, SELL, TQ1

---

Galerie der Validierungsdaten

• 

  FC experiment of human peripheral blood lymphocytes using 65167-1-Ig

  1X10^6 human peripheral blood lymphocytes were surface stained with 0.5 ug Anti-Human CD62L (65167-1-Ig, Clone: DREG56) (green) or 0.5 ug isotype control antibody (black), and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). Cells were not fixed.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane Lymphozyten aus peripherem Blut

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65167-1-Ig bindet in FC CD62L und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / Mouse IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: PMA-aktivierte humane Leukozyten aus peripherem Blut
• Vollständiger Name: selectin L
• Berechnetes Molekulargewicht: 42 kDa
• GenBank-Zugangsnummer: BC020758
• Gene symbol: SELL
• Gene ID (NCBI): 6402
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Mit Protein-A-Affinitätschromatographie gereinigt
• Lagerungspuffer: PBS mit 0,1% Natriumazid.
• Lagerungsbedingungen: Bei 2-8℃ lagern.

Hintergrundinformationen

CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).