Properdin/PFC Monoklonaler Antikörper

Properdin/PFC Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1D5A9

Kat-Nr. : 66788-1-Ig

Synonyme

CFP, 1D5A9, BFD, Complement factor P, complement factor properdin

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  WB analysis of Jurkat using 66788-1-Ig

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human plasma using 66788-1-Ig

  human plasma were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Jurkat-Zellen, human plasma

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

66788-1-Ig bindet in WB, ELISA Properdin/PFC und zeigt Reaktivität mit Hausschwein, human, Ratten

• Getestete Reaktivität: Hausschwein, human, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Properdin/PFC fusion protein Ag9798
• Vollständiger Name: complement factor properdin
• Berechnetes Molekulargewicht: 469 aa, 51 kDa
• Beobachtetes Molekulargewicht: 50 kDa, 100 kDa, 150 kDa
• GenBank-Zugangsnummer: BC015756
• Gene symbol: CFP
• Gene ID (NCBI): 5199
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CFP, also named as Properdin or PFC, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.