CXCL2 Rekombinanter Antikörper

CXCL2 Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC (Intra)

Konjugation

APC Fluorescent Dye

CloneNo.

242007G5

Kat-Nr. : APC-FcA98259

Synonyme

C-X-C motif chemokine 2, Macrophage inflammatory protein 2, MIP2, Mip-2, Scyb2

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  FC experiment of RAW 264.7 using APC-FcA98259

  1x10^6 untreated (left) or LPS and Brefeldin A treated (right) RAW 264.7 cells were intracellularly stained with 0.1 ug APC Anti-Mouse CXCL2 Rabbit RecAb (APC-FcA98259, Clone: 242007G5). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC (Intra): mit LPS und Brefeldin A behandelte RAW 264.7-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

APC-FcA98259 bindet in FC (Intra) CXCL2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCL2 fusion protein Eg2239
• Vollständiger Name: chemokine (C-X-C motif) ligand 2
• Berechnetes Molekulargewicht: 11 kDa
• GenBank-Zugangsnummer: NM_009140
• Gene symbol: Cxcl2
• Gene ID (NCBI): 20310
• Konjugation: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CXCL2 is a member of the CXC subfamily, which encodes secreted proteins involved in immunoregulatory and inflammatory processes. CXCL2 is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. CXCL2 plays a critical role in maintaining cancer-induced macrophage infiltration and the resulting mechanical hypersensitivity and persistent spontaneous nociception (PMID: 36754246).