Complement factor B Monoklonaler Antikörper

Complement factor B Monoklonal Antikörper für IF-P

Wirt / Isotyp

Maus / IgM

Getestete Reaktivität

human

Anwendung

IF-P

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

8D2B6

Kat-Nr. : CL488-66154

Synonyme

BF, BFD, C3/C5 convertase, CFAB, CFB, complement factor B, FB, FBI12, GBG, Glycine rich beta glycoprotein, H2 Bf, PBF2, Properdin factor B

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  IF Staining of human liver using CL488-66154

  Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CoraLite® Plus 488 Complement factor B antibody (CL488-66154, Clone: 8D2B6 ) at dilution of 1:200.

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  IF Staining of human liver using CL488-66154

  Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CoraLite® Plus 488 Complement factor B antibody (CL488-66154, Clone: 8D2B6 ) at dilution of 1:200.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: humanes Lebergewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

CL488-66154 bindet in IF-P Complement factor B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgM
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Complement factor B fusion protein Ag19107
• Vollständiger Name: complement factor B
• Berechnetes Molekulargewicht: 86 kDa
• Beobachtetes Molekulargewicht: 93 kDa
• GenBank-Zugangsnummer: BC007990
• Gene symbol: Complement factor B
• Gene ID (NCBI): 629
• Konjugation: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Form: Liquid
• Reinigungsmethode: Thiophiler Affinitätschromatograph
• Lagerungspuffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is cleaved into Ba and Bb by factor D in the presence of C3b. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.