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Fibrinogen Beta Chain Monoklonaler Antikörper

Fibrinogen Beta Chain Monoklonal Antikörper für WB,ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB,ELISA

Konjugation

Unkonjugiert

CloneNo.

1F8E4

Kat-Nr. : 66186-1-Ig

Synonyme

FGB, fibrinogen beta chain

Galerie der Validierungsdaten

Filter:
  • Western Blot (WB) analysis of human heart tissue using Fibrinogen Beta Chain Monoclonal antibody (66186-1-Ig)

    WB analysis of human heart using 66186-1-Ig

    human heart tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of fetal human brain tissue using Fibrinogen Beta Chain Monoclonal antibody (66186-1-Ig)

    WB analysis of fetal human brain using 66186-1-Ig

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Erfolgreiche Detektion in WBhumanes Herzgewebe, fetales humanes Hirngewebe

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

WBSee 1 publications below

Produktinformation

66186-1-Ig bindet in WB,ELISA Fibrinogen Beta Chain und zeigt Reaktivität mit human

Getestete Reaktivität human
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen Fibrinogen Beta Chain fusion protein Ag10205
Vollständiger Name fibrinogen beta chain
Berechnetes Molekulargewicht 491 aa, 56 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC107766
Gene symbol FGB
Gene ID (NCBI) 2244
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGB is the beta chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide B is cleaved from FGB by thrombin. Mutations in the gene of FGB lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Protokolle

Produktspezifische Protokolle
WB protocol for Fibrinogen Beta Chain antibody 66186-1-IgProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanWB

Ann Transl Med

LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.

Authors - Yue Guan
View Article