FceR1 Monoklonaler Antikörper

FceR1 Monoklonal Antikörper für FC

Wirt / Isotyp

Armenian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

MAR-1

Kat-Nr. : 65091-1-Ig

Synonyme

Fce1a, fcepsilonri, FceR1, Fcer1a, FcERI, Fcr 5

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Galerie der Validierungsdaten

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  FC experiment of MC/9 using 65091-1-Ig

  1X10^6 MC/9 cells were surface stained with 0.25 ug Anti-Mouse FceR1 (65091-1-Ig, Clone: MAR-1) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (green), or stained with 0.25 ug Armenian Hamster IgG isotype control and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: MC/9-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65091-1-Ig bindet in FC FceR1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Armenian Hamster / IgG
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: Fc receptor, IgE, high affinity I, alpha polypeptide
• GenBank-Zugangsnummer: BC125455
• Gene symbol: Fcer1a
• Gene ID (NCBI): 14125
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS mit 0,1% Natriumazid, pH 7,3.
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

Fc epsilon Receptor I alpha (FceRIa) is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FceRIa forms a tetrameric complex with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).