FceR1a Monoklonaler Antikörper

FceR1a Monoklonal Antikörper für FC

Wirt / Isotyp

Armenian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

MAR-1

Kat-Nr. : CL488-65091

Synonyme

MAR-1, High affinity immunoglobulin epsilon receptor subunit alpha, Fcr 5, FcERI, FceR1

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  FC experiment of MC/9 using CL488-65091

  1X10^6 MC/9 cells were surface stained with 5 ul CoraLite® Plus 488 Anti-Mouse FceR1 (CL488-65091, Clone:MAR-1) (green) or CoraLite® Plus 488 Armenian Hamster IgG isotype control (black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: MC/9-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL488-65091 bindet in FC FceR1a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Armenian Hamster / IgG
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: Fc receptor, IgE, high affinity I, alpha polypeptide
• GenBank-Zugangsnummer: BC125455
• Gene symbol: FceR1a
• Gene ID (NCBI): 14125
• Konjugation: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).