FceR1a Monoklonaler Antikörper

FceR1a Monoklonal Antikörper für FC

Wirt / Isotyp

Armenian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

MAR-1

Kat-Nr. : PE-65091

Synonyme

MAR-1, High affinity immunoglobulin epsilon receptor subunit alpha, Fcr 5, FcERI, FceR1

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  FC experiment of MC/9 using PE-65091

  1X10^6 MC/9 cells were surface stained with 0.13 ug PE Anti-Mouse FceR1 (PE-65091, Clone: MAR-1) (red) or 0.13 ug isotype control antibody (black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: MC/9-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-65091 bindet in FC FceR1a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Armenian Hamster / IgG
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: Fc receptor, IgE, high affinity I, alpha polypeptide
• GenBank-Zugangsnummer: BC125455
• Gene symbol: FceR1a
• Gene ID (NCBI): 14125
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.1% gelatin
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).